With the increase of the overall volume of air traffic and enhanced navigation precision, wake turbulence encounters in the en-route phase of flight above 10 000 feet (ft) mean sea level (MSL) have progressively become more frequent in the last few years. The aim of this SIB is to enhance the awareness of pilots and air traffic controllers of the risks associated with wake turbulence encounters in the en-route phase of flight and provide recommendations and advisories with the purpose of mitigating the associated risks.