This document provides guidance on how to capture the safety data related to the reported occurrences in the AST. Each year States are required to send the following AST reports: A report containing the consolidated data of the previous year, including updated data for the first six months of that previous year by the end of March of each year; A report containing initial data covering the first six months (January-June inclusive) of the respective year by the end of September and an updated report for the full previous year (if applicable); A report containing updates of any previously submitted reports; Updates of AST reports older than 2 years not captured in previous submissions or other updated AST reports are welcomed at any time.